BIPN 150 Lecture Notes - Lecture 14: Neurodevelopmental Disorder, Observation, Heredity
Document Summary
11:45 pm: asd, different behavioral manifestations of disorders, but similar genomics, mood disorders have strong genetic risk factors. In-utero + environment --> complex disorders manifest later after birth. Repetitive or hyper-focused behaviors/ interests: male: female diagnoses may be because of underdiagnoses in females. Cultural expectations in females/ males don"t align to diagnoses. Widely expected there is biological difference in diagnoses rates. Cannot be linked to chromosome deficiencies (not x-linked) --> genetic pattern of heredity doesn"t confer. Presence of male hormones = genetic and environmental influences (metabolites/ too much testosterone exposure: degree of intellectual ability varies in asd. High functioning vs classic autism: no gross anatomical abnormalities or physical impairment/ biomarkers between autistic and normal brains, diagnoses is subject to observational bias, autistic behaviors not reflective of a disease --> is a condition. Autistic behaviors reflected in normal people: but if an individual is impaired in living --> have disorder, comorbid asd symptoms.
