MCDB 1A Lecture Notes - Lecture 7: Kinesin, Genetic Diversity, Motor Protein

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Cdks and cyclins always work together: so, the synthesis and degradation of different cyclins controls the activity of different cdks, when active, cdks add phosphate groups covalently to cell cycle control proteins (there are many such proteins). Some cell cycle proteins are active when phosphorylated, others are inactive: there are several cyclin-cdk pairs each pair acts at a different stage of the cell cycle to control progression through the cycle. Picture: g2-m cyclin-cdk regulates entry into m; cyclin is made during g2, m cyclin-cdk"s: regulate progress through mitosis, g1-s phase cyclin-cdk"s regulates entry beyond the restriction point, there are more, but don"t have to know them. Important features of chromatin structure: basic building block unit is a 10 nm in diameter, called a. Pictures: when cell wants to divide, it gets even more compacted, diameter starts at a/b 2 nm, then condenses to 1400 nm. Meiotic chromosomes: chromosomes look different from each other.

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