PNB 2265 Lecture Notes - Lecture 10: Immunoglobulin A, Vascular Resistance, Histology
16 Aug 2018
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Document Summary
Pathway for the movement of in and out of lungs: plumbing. At the same time: conduit for smell, speech, protection against dehydration, t swings, pathogens, regulation of blood pressure. Automatic and under conscious control: sleeping vs talking. Gas exchange: oxygen in and co2 out. Upper respiratory track: nose and sinuses, moisten, warm and filter air, large number of capillaries bloody nose, pharynx, common pathway for food and air, tonsils (immune) Lower respiratory track: larynx, voicebox, vibrations lead to sound, trachea, pathways to lungs, mucosa, submucosa, adventitia and muscle, bronchi, bronchioles, all the way to alveoli. Macrophages eating debris: the air we breathe is dirty. Iga is found here: trap dirt in airways (trachea, pharynx) but does not stimulate inflammation. Nose to pharynx: pseudostratified, ciliated and columnar epithelium, goblet cells. Pharynx to bronchi: stratified squamous epithelium. Direct contact with exterior: tight junctions, polarized cells, stem cells. Designed for the same level of protection given to integumentary system.
