NURS 3220 Lecture Notes - Lecture 19: Gallstone, Itch, Hypotension
Document Summary
Atherosclerosis associated with: high serum ldl, low hdl, high homocysteine levels (decreased with folic acid, vit b6, vit b12, high vldl (contain triglicerides, high triglycerides (tg, high c-reactive protein (crp)- predictor of heart disease! Atherosclerosis causes: heart: coronary artery disease (cad, angina pectoris, myocardial infarction, brain: tia, stroke, carotid artery disease, kidneys: decrease gfr rate, hypertension, renal failure, peripheral artery disease (pad, death and disability. Which factor is most important to change to reduce atherosclerosis: a. hdl, b. homocysteine, c. ldl, d. triglycerides. How can we decrease ldl: decrease ldl production: rate limiting enzyme is hmg coa reductase, bind dietary fats so they are not absorbed, triggering movement of ldl to liver. Side effects of many drugs that lower ldl: liver: liver damage, esp. statins, avoid with damaged liver, check baseline liver enzymes, muscle: myopathy leading to muscle pain, extreme is rhabdomyolitis, associated with renal.
