MCB 2210 Lecture Notes - Lecture 25: Hydroxyproline, Collagen, Tripeptide
1 Dec 2016
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Document Summary
Cell-cell & cell-matrix connections: animal cells can be organized into tissues, five major tissue types: Blood: cells in tissues interact with one another and with the extracellular environment, these connections are important for allowing cells to aggregate into distinct tissues and for the bi-directional processes including: Connects actin filament bundle in one cell with that in the next cell. Connects intermediate filaments in one cell to those in the next cell. Allows passage of small water-soluble molecules cell to cell. Anchors intermediate filaments in a cell to extracellular matrix. Focal adhesions (focal contacts: cell-cell adhesions involve cis (same side) and trans (opposite side) interactions, cell adhesion molecules (cams) can generation very tight adhesion when many weak interactions are combined (like velcro) Major families of cell adhesion molecules (cams: cellular adhesions are controlled by homophilic and heterophilic interactions, cadherins form homophilic cross-bridges between adjacent cells.
