BIO SCI 9A Lecture Notes - Lecture 6: Insulin Resistance, Atorvastatin, Cardiovascular Disease
6 Sep 2016
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Document Summary
Vldl (very low-density lipoproteins: composed primarily of triglycerides, made by the liver, transport lipids to the tissues, get smaller and denser as triglyceride portion is removed. Ldl (low-density lipoproteins: composed primarily of cholesterol, transport lipids to the tissues. Hdl (high-density lipoproteins: composed primarily of protein, transport cholesterol from the cells to the liver. Blood lipid profile: reveals concentrations of lipids in the blood. Desirable levels: total cholesterol < 200mg/dl, ldl cholesterol < 100 mg/dl, hdl cholesterol > 60 mg/dl, triglycerides < 150 mg/dl. Factors that lower ldl and raise hdl: weight control, replace saturated fat with monounsaturated fat and polyunsaturated fat in the diet, soluble fibers, phytochemicals, moderate alcohol consumption, physical activity. Risk from trans fats: higher ldl cholesterol, lower hdl cholesterol. Risks from dietary cholesterol: less effect on blood cholesterol than saturated fat and trans fat. Heart disease: elevated ldl is a risk factor for cvd, cholesterol accumulates in the arteries, restricts blood flow, and raises blood pressure.
