BIO SCI 97 Lecture 7: Lecture 7 Notes

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Autosomal - dna that is inherited from any cell that is not a sex cell. The 23rd pair are the sex chromosomes. Autosomal inheritance - refers to transmission of genes carried on autosomes, chromosomes found in both males and females. There are two copies of each autosome in a diploid organism, one from the mother and one from the father. Autosomal traits are caused by genes on autosomes and categorized as either autosomal recessive or autosomal dominant. Sry - mammalian sex determination is initiated by sry. A region on the y chromosome associates with male sex determination. A gene on the y chromosome leads to the development of male characteristics. Mitochondrial chromosome - most mitochondrial proteins are encoded by nuclear dna. Mtdna exists as a circular chromosome with 37 genes. Disorders that affect the mitochondria can be due to mutations in the nuclear genome or mutations in the mtdna. All mtdna is maternal derived - deposited in the egg.

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