BIO SCI 97 Lecture Notes - Lecture 2: Tata Box, Guanosine, Intron

49 views4 pages

harlequinrhinoceros187

2 Apr 2018

School

Department

Course

Professor

For unlimited access to Class Notes, a Class+ subscription is required.

Document Summary

Many factors regulate transcription initiation/gene expression in eukaryotes: dna bend dozens to thousands of base pairs, activator proteins, co-activator proteins: interact with polymerase and start it, rna polymerase 2, transcription start, tata box present at -30. The tata box binds to the complete initiation complex: complete initiation complex. It"s more dif cult to identify where genes are. The regulation of genes in multicellular eukaryotes is more complex because you have to turn them on and off. The promoter determines where transcription starts and the direction in which it proceeds: when polymerase binds to the promoter, it binds with a speci c orientation. Genes are present on both strands of dna. Termination sites are usually located such that transcribed regions do not overlap. The primary transcript is processed into mrna in eukaryotes. The processed transcript has a 5" methyl guanosine cap and at the end there is a poly. Introns are spliced out and turned into discarded introns.

Related Questions

1 DNA sequences found in introns provide [A] amino acid sequence information.

[B] regulatory information.
[C] no known useful information.

[D] structure for the gene.
[E] alternative DNA splicing possibilities.

3. The TATA box is a(n)
[A] sequence close to the promoter region of many genes.
[B] square-shaped sequence.
[C] enhancer consensus sequence.
[D] activator sequence necessary for proper translation.
[E] None of the above

5. Regarding genes and gene expression, which of the following is not a difference between prokaryotes and eukaryotes
[A] Eukaryotic DNA does not contain a TATA box close to the initiation site as does prokaryotic DNA.

[B] In eukaryotes, RNA polymerase requires

'transcription factors'or initiation.

[C] Prokaryotic genes are often grouped together in

operons.

[D] In eukaryotes, the regulation of several genes at once requires common control elements in each of the genes.
[E] There is a diversity of eukaryotic polymerases that is reflected in the diversity of eukaryotic promoters.

10) In eukaryotic cells, a repressor

[A] is made of DNA.
[B] binds to the enhancer region to block transcription. [

C] is located both upstream and downstream from the promoter.
[D] binds to the operator to block RNA polymerase.

[E] binds to a silencer to reduce transcription rates.

Coordinated regulation of genes in eukaryotic cells [A] is the result of positioning the same regulatory sequence in front of each gene.
[B] results from all of those genes being under the control of one promoter.

[C] occurs because related genes all have the same

operons.
[D] occurs because enhancers cause DNA to bend.

1. A region of a chromosome contains two strands of DNA, yet only one is used to transcribe a gene because

A. all genes are found on the same strand of DNA in a chromosome.

B.both strands are transcribed, but only one strand of DNA contains a reading frame.

C.RNA polymerase binds to the terminator, stopping transcription on one strand of DNA.

D.RNA polymerase binds to the promoter, which precedes the gene only on the template strand of DNA.

E.the start of transcription is random along the chromosome and doesn't always occur on a gene.

2. In eukaryotes an mRNA molecule can only be translated by one ribosome at a time.

True or False

3.The process by which cells use the information of RNA molecules to make proteins is transcription.

True or False

Which of the following statements is true?

A.) Molecules of mRNA are translated from 3' to 5'

B.) For each amino acid found naturally in proteins, there is only one codon in the genetic code.

C.)The Shine-Dalgarno sequence is found in the promoters of genes in both prokaryotic and eukaryotic organisms.

D.) During translation, both strands of DNA are used as templates for the construction of two new strands of protein.

E.) When considering the initiation of transcription one often finds consensus sequences, such as the TATA box, located in the region of the DNA where RNA polymerase(s) bind.

BIO SCI 97 Lecture Notes - Lecture 2: Tata Box, Guanosine, Intron

Document Summary

Get access

Related textbook solutions

Molecular Cell Biology

Biology: Science for Life with Physiology

Biology

Concepts of Biology

Essentials of Biology

Related Documents

BIO SCI 97 Lecture Notes - Meiosis, Gene Silencing, Repressor

BIO SCI 97 Lecture 3: Lecture 3 Notes

MBB 222 Lecture Notes - Lecture 27: Tata Box, Bioinformatics, Enzyme

Related Questions