BIO SCI 97 Lecture 13: Bio 97 Lecture 13

34 views4 pages

sapphirejellyfish386

11 Sep 2017

School

Department

Course

Professor

For unlimited access to Class Notes, a Class+ subscription is required.

Document Summary

Population genetics aims to make quantitative approaches of allele frequencies and genotype frequencies. Population: group of organisms of the same species living in the same geographical area. Genotype frequency: proportion of individuals in a population with a specific genotype. Allele frequency: proportion of alleles in a population. All the genotypic frequencies should = 1. All allelic frequencies add up to = 1. P = frequency of a (big allele) Q = freq of a (small allele) Calculating allele frequencies given genotype frequency (gf) Assume 100 people in the population 200 alleles. In the example using generation x, you have 49 people with aa, 42 with aa, and. 49(2) = a allele from 49 people with aa, etc. Calculating allele frequencies given genotype frequency (gf) -- shorter method. ^both above methods work whether you"re in hwe or not. Hardy-weinberg equation: predict what af"s and gf"s will be in future generations.

Related Questions

Part A

In humans, individuals may or may not have a widowâs peak. This trait is controlled by genes at a single locus, with the allele for having a widowâs peak dominant to the allele for not having one. A population of humans is sampled; 59 have a widowâs peak and 44 do not. 25 of the people with a widowâs peak are homozygous dominant. What are the frequencies of the dominant and recessive alleles observed in this sample?

p = _____

q = _____

Part B

In a species of corn, individuals have either narrow or wide corn cobs. This trait is controlled by genes at a single locus, with the narrow cob allele dominant to the wide cob allele. A farmer counts 74 narrow cob and 113 wide cob plants in a field. Of the narrow cob plants, 28 are homozygous dominant. What are the frequencies of the dominant and recessive alleles observed in this sample?

p = _____

q = _____

Part C

In a population of peas, the frequency of the dominant allele for a purple flower is 0.61 and the frequency of the recessive allele for a white flower is 0.39. What would the genotypic frequencies be if the population is in equilibrium?

_____ = Frequency of homozygous dominant individuals

_____ = Frequency of heterozygous individuals

_____ = Frequency of homozygous recessive individuals

How many individuals would you expect of each genotype in a population of 500 peas?

_____ = Number of homozygous dominant individuals

_____ = Number of heterozygous individuals

_____ = Number of homozygous recessive individuals

Part D

In mice, a mahogany coat color allele is dominant over the tan coat color allele. In a population of mice, the frequency of the allele for mahogany coat color is 0.19 and the frequency of the allele for tan coat color is 0.81. What would the genotypic frequencies be if the population is in equilibrium?

_____ = Frequency of homozygous dominant individuals

_____ = Frequency of heterozygous individuals

_____ = Frequency of homozygous recessive individuals

How many individuals would you expect of each genotype in a population of 100 mice?

_____ = Number of homozygous dominant individuals

_____ = Number of heterozygous individuals

_____ = Number of homozygous recessive individuals

Part E

In humans, the free earlobe allele is dominant over the attached ear lobe allele. In a population of humans, the frequency of the allele for free earlobes is 0.42 and the frequency of the allele for attached earlobes is 0.58. What would the genotypic frequencies be if the population is in equilibrium?

_____ = Frequency of homozygous dominant individuals

_____ = Frequency of heterozygous individuals

_____ = Frequency of homozygous recessive individuals

How many individuals would you expect of each genotype in a population of 25 humans?

_____ = Number of homozygous dominant individuals

_____ = Number of heterozygous individuals

_____ = Number of homozygous recessive individuals

rubyleopard160

Q1. What are alleles?Different forms of the same gene.Different genes.The different characteristics of an organism.Genes found only in humans.Q2. If you add up the frequency of homozygotes + the frequency of heterozygotes for one gene (i.e. at one locus) in a population, what number do you get?Q3. People who are heterozygous for the sickle-cell allele:Are susceptible to malaria but not sickle-cell anemia.Are susceptible to sickle-cell anemia but not malaria.Are not susceptible to either sickle-cell anemia or malaria.Are susceptible to both sickle-cecell anemia and malaria.Q4. In the case study in this lab, which genotype is represented by "2pq" in the Hardy-Weinberg equation?Homozygous HbAHomozygous HbSHeterozygous HbA/HbSNo specific genotypeQ5. Suppose that, in an isolated village, the proportion of individuals that have sickle-cell anemia is 0.1 (or 1 of every 10 people). What proportion of the population should be sickle-cell carriers, according to Hardy-Weinberg expectations?Q6. When you simulated the elimination of malaria at the beginning of the lab, once the allele frequencies stabilized, what was the frequency of the HbA allele?Q7. When you investigated regional differences, what was the frequency (over many generations) of the HbS allele in the village in the "slightly wet" part of Africa?Q8. What is the number of deaths due to sickle-cell anemia in a region without mosquitoes expected to be?Very lowVery highModerateRelated to the frequency of malaria allelesQ9. As long as there are multiple alleles of a gene in a population, why will the frequencies of the alleles always change over time?Because natural selection changes all allele frequencies in populations over time.Because genetic drift causes random fluctuations of allele frequencies in populations.Because diseases will eliminate some of the alleles, generating fluctuations in their frequencies.Because allele frequencies fluctuate before the alleles eventually become fixed.Q10. Imagine a huge population with a gene that has ten functionally equivalent, neutral alleles. A small but genetically representative group of individuals from the big population is transported to an island, forming a small population. Which of the statements below best describes what will likely happen over time, and why?Because natural selection doesn't act on neutral alleles, the frequencies in the two populations should remain the same over time.Genetic drift will cause one allele to first become fixed in the island population, and later to become fixed in the original, large population.Genetic drift will result in the allele frequencies of the two populations diverging over time, with alleles being lost sooner in the island population.The allele frequencies of the two populations will change similarly due to a combination of genetic drift natural selection.

indigosnake469

Hemoglobin and Fitness Instructions Directions: Neutral Evolution

1. Obtain 20 beans of two different colors (e.g., white and red). Count out 16 white and 4 red beans. The white beans represent the Hn allele and the red beans represent the Hs allele. This is the genetic makeup of your starting population. (Note: You can use any objects that can readily be categorized into two groups, such as coins, colored rocks, or paper clips.)

2.Calculate the frequency of both alleles [f(Hn) and f(Hs)] and record them in Table 1. In our experiment frequency is a measure of how many copies of a given allele exist in the gene pool (i.e., a proportion). Use decimal values. â¨

3.Arrange the beans into pairs. These pairs represent the genotype of each of 10 individuals in the population. Record the number of individuals with each genotype [f(Hn Hn), f(Hn Hs), and f(HsHs)] in Table 1. â¨

4.Now imagine that the individuals are living and reproducing with each individual reproducing at the same rate (i.e., all individuals produce two copies of each of their alleles into the next generation). Obtain enough beans to represent the next generationâ the offspring generationâand then let the parental generation âdieâ. â¨

5.Calculate the frequency of each allele in the offspring generation and record it in Table 1. â¨

Answer the questions that follow in Table 1. â¨

Table 1

	f(HnHn)	f(HnHs)	f(HsHs)	f(Hn)	f(Hs)
oiginal generation
offspring generation

Answer the following questions to help you understand the exercise:

What happened to the frequency of the common allele? â¨

What happened to the frequency of the rare allele? â¨

What happened to the frequency of the common and rare alleles when the starting frequencies were different from yours

What happens to allele frequencies from one generation to the next if there are no evolutionary forces acting on the population? â¨

greyotter669

BIO SCI 97 Lecture 13: Bio 97 Lecture 13

Document Summary

Get access

Related textbook solutions

Molecular Cell Biology

Biology: Science for Life with Physiology

Concepts of Biology

Biology

Essentials of Biology

Related Documents

BIO SCI 97 Chapter Notes -Allele Frequency, Microevolution

BIO SCI 97 Lecture 10: Lecture 10 Notes

BIO SCI 97 Lecture 21: Lecture 21 Notes

Related Questions