BIO SCI 93 Lecture Notes - Lecture 14: Protein Kinase, Platelet-Derived Growth Factor, S Phase

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BIO SCI 93 Full Course Notes
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BIO SCI 93 Full Course Notes
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93stop appear to stop cell cycle progression near end of g1 or very beginning of s phase. 93stop does stop cell cycle progression at a specific stage. Why would an inhibitor stop cell cycle progression at a specific stage. How does a cell control and regulate the cell cycle. Checkpoints are critical points where stop and go signals regulate the cycle. There is a mitotic checkpoint where it stops. 93stop checkpoint triggered the g1, which would trigger the s phase, where replication occurs. If something goes wrong, the g0 state would be triggered to stop the cell cycle. You can"t come back from the cell cycle. If the cell can"t be fixed, the cell gets destroyed. Takes a lot to get cell cycle to be in g0 state. Growth factors are proteins that triggers the cell to go through the cell cycle. Protein kinases give go-ahead at g1 and g2 checkpoints.

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