BIO SCI 93 Lecture Notes - Lecture 19: Sister Chromatids, Kinetochore, Karyotype

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BIO SCI 93 Full Course Notes
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BIO SCI 93 Full Course Notes
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Division of gamete cells used in sexual reproduction. Somatic cells of each species contains a specific number of chromosomes. Human cells 46 chromosomes; 23 homologous chromosomes. Chromosomes arranged in pairs- maternal and paternal homologs. Chromosomes vary in size- different number of genes. Each chromosome consists of single dna molecule and associated histone proteins. Dna not visible at level of light microscope; dna must be condensed. Position of centromere (kinetochore) can vary- sometimes in middle, can also be asymmetrical. Chromosomes show banding patterns due to chromosomal proteins. Chromosomes in diploid parent cell duplicate forming two homologous chromosomes. Chiasmata; crossing over/swap of genes between homologous chromosomes. Cytoplasm separates and two cells are formed (sister chromatids) Haploid cells created are genetically distinct from one another and their parent cells. Sister chromatids line up along the metaphase plate. Cytoplasm separates and 4 haploid cells are created. Variability in meiosis- more chromosome pairs; more variation!

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