BIO SCI 38 Lecture Notes - Lecture 1: Synaptic Plasticity, Pyramidal Cell
13 Jan 2020
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Document Summary
Depth recording can measure the activity of a single neuron. Even with its great sensitivity, the smallest measurable magnetic field changes detectable by meg are thought to be produced by 50,000 pyramidal neurons. The resolution of fmri is limited by the density of capillaries in the brain and will never exceed this. We are effectively at the limit of fmri resolution at ~ 0. 55 mm. The experience used to induce ltp is a low-intensity high-frequency electrical event that bypasses all the sensory inputs that normally bring environmental information into the brain. Ltp electrically induced in tissue slices or in the brain does not represent a behavioral experience. Thus, knowledge gained from the studies of synaptic plasticity is best viewed as the fundamental source of hypotheses about how the brain makes memories. Memories are the product of behaving organisms interacting with their environments.
