BIO SCI 35 Lecture Notes - Lecture 13: Noxious Stimulus, Postcentral Gyrus, Capsaicin
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Fire and spice: pressure, temperature and noxious stimuli. Fooling touch with vision: behavioral therapy for phantom limb pain. Capsaicin binds to thermoreceptors and will activate hot receptors and fool the system to think its hot. Menthol binds to thermoreceptors and will activate cool receptors and fool the system to think its cool. Capsaicin bind to slow conducting nociceptor and stimulates it. The cells use up all their substance p. If nociceptors damaged, the neurons might still fire even when no stimulus (injury), so feel pain even when not injured. Receptive field varies by type of somatosensory signal. Feeling pain from a limb that does not exist ( or ) The mirror box - visual therapy for phantom pain. There is a center-surround organization of receptive fields. We use them to sense what is around us. Forms a map of the world around us.