BIO SCI 35 Lecture Notes - Lecture 3: Luigi Galvani, Bioelectromagnetics, University Of Manchester
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A neuroanatomist that discovered bioelectricity or galvanism - or the study of electrophysiology. In 1849, while at konigsberg, helmholtz measured the speed at which the signal is carried along a nerve fibre using a galvonometer. 24. 6-38. 4 m/sec (about the speed of a fast race car - not too fast, not too slow either) Correctly proposed that excitable cells are surrounded by a membrane selectively permeable to k+ ions at rest and that during excitation the membrane permeability to other ions increases. For every 2 potassium in, 3 sodium out. Makes the inside negative compared to the outside/makes outside more positive. The number of positive charges on the outside is > than the number of positive charges on the inside. An increase in the magnitude of the membrane potential. When potassium channels are open - potassium goes out of the cell - the inside gets less positive. A reduction in the magnitude of the membrane potential.