BIS 2B Lecture Notes - Lecture 13: Allele Frequency, Gene Flow, Malaria

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Mutations rare on a per locus basis usually deleterious point or chromosomal, multiple forms of each integral for evolution. If as heterozygosity confers increased survivorship from malaria, then the s allele should peak in frequency with malaria exposure. Prediction: allele frequency should respond to exposure to malaria. If ss confers increased mortality because of anemic conditions, and anemia mortality can be influenced by healthcare, then the frequency of the s allele should vary with socio-economic status. Wealthier places should tolerate" greater incidence of the s allele. Gene flow results from the migration of individuals and gametes (or other propagules like seeds or larvae) from one population to another, and the incorporation (by successful breeding) of the genes they carry into the novel gene pools. Immigration (arrival) of individuals from another population with different gene frequencies into a recipient population. Has an especially large effect if the recipient population is small. (departure) of individuals out of a population.

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