BIO 479 Lecture Notes - Lecture 2: Giant Panda, Endocrinology, Parachuting

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Maintain homeostasis meet every energy demand, regulate energy reserves. Di erent internal ac(cid:2210)vi(cid:2210)es within itself and it ac(cid:2210)vi(cid:2210)es with the external. Applied context: maintain human, domes(cid:2210)c animal, wildlife health. Most medical/veterinary problems have endocrine basis. Prac(cid:2210)(cid:2210)oners can specialize: treat pa(cid:2210)ents having problems with growth & development, metabolism (cid:336)diabetes, thyroid(cid:337), behavior/depression. Ex: smithsonian na(cid:2210)onal zoo jogayle howard. Manipulated female panda to go into heat when it normally wouldn"t. Compara(cid:2210)ve endocrinologists: look at similar/di erences across popula(cid:2210)ons or species to ask how(cid:336)mechanisms(cid:337) and why (cid:336)adap(cid:2210)ve signi cance(cid:337) Behavioral/ecological endocrinologist: integrate behavior, physiology, and ecology (cid:336)human, non-human(cid:337) Microarrays preset traps on a slide. Measuring hormone biosynthesis ac(cid:2210)vity (cid:336)usually by measuring p (cid:403)(cid:404)0 enzymes(cid:337) Mapping hormone receptor density and distribu(cid:2210)on histology. Methods for manipula(cid:2210)ng hormone ac(cid:2210)vity , ex: sky diving and stress. Data: plasma levels of cor(cid:2210)sol are posi(cid:2210)vely correlated with ight al(cid:2210)tude in humans. Correla(cid:2210)on between cor(cid:2210)sol (cid:336)stress(cid:337) and height (cid:336)al(cid:2210)tude(cid:337)

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