BIOL 1081 Lecture Notes - Lecture 28: Chloroplast, Genomic Imprinting, Sister Chromatids

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19 Sep 2017
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Chromosomal abnormalities & non-mendelian inheritance reading: sections 15. 4-15. 5 in textbook: define nondisjunction and aneuploidy, describing the most common consequences in humans. Aneuploidy: if either of the aberrant gametes unites with a normal one at fertilization, the zygote will also have an abnormal number of a particular chromosome. Deletion: occurs when a chromosomal fragment is lost. The affected chromosome is then missing certain genes. Duplication: when the deleted fragment becomes attached as an extra segment to a sister chromatid. Inversion: a chromosomal fragment many also reattached to the original chromosome but in the reverse orientation. Translocation: the fragment joins a nonhomologous chromosome: describe what genomic imprinting is, including the mechanism involved. Because these genes are imprinted differently in sperm and eggs, the offspring expresses only one allele of an imprinted gene, the one that has been inherited from either the female or the male parent.

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