PSIO 303A Lecture Notes - Lecture 35: Nuclear Membrane, Nuclear Pore, Rna Splicing

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Block 3 - lecture 5 - genetic overview. Rna splicing (all figures are provided by dr. delamere) Transcription and translation can handle the wealth of info provided by dna. Overall steps in protein synthesis: errors we use ribosomes to help make the mrna from dna template. Dna is template used to make mrna in the nucleus. Mrna exits the nucleus to the ribosomes. Trna molecules brings amino acids to the ribosome. Ribosomes move along the mrna strand and make proteins (polypeptide chains which are peptide bonds that connect neighboring amino acids). Mrna is able to move out of the nucleus to cytoplasm via nuclear pore. Dna strand containing a specific gene serves as a template strand. Rna nucleotides are matched to complimentary dna bases. Mrna molecule is complete and dna rewinds. Rna polymerase: when it finds the right place on dna (guided by promoter), moves down the ssdna and makes the copy of mrna.

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