MIC 301 Lecture Notes - Lecture 15: Antigen Presentation, Dendritic Cell, Immune System

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Bubble boy was boy with scid but today we can use transplant to avoid this happening again. Hiv = most common secondary (acquired) immunodeficiency. Slide 13 definitions: immune = latin for exempt, immune system = cells dedicated to fighting pathogens, immunity = post infection. Capacity to protect in the future against that specific pathogen: pathogen = replicating organism that causes diseases (non-infectious pathogens include toxins that are secreted and we neutralize them so they don"t replicate. Immune system deals with different types of pathogens in different locations: slide 16 and 17 show this. Immune system must be able to deal with very fast replication of bacteria and viruses: bacteria = extracellular and viruses = intracellular. Antigen presentation is key because can show immune system what they contain. 21: adaptive is b and t cells and innate is rapid response. 3: barriers are 1st layer of protection and they are non-specific and breaching of a barrier leads to an immune response.

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