BSCI 223 Lecture Notes - Lecture 8: Thermodynamics, Antiseptic, Triclosan
Document Summary
Pentose phosphate pathway: an alternative to glycolysis for glucose catabolism, produces energy, but is important for the production of precursor metabolites, ribose 5p (nucleotides, erythrose 4p (amino acids, to build a cell, you need 12 precursor metabolites. Energy produced: aerobic respiration, uses oxygen as final electron acceptor, anaerobic respiration, uses other final electron acceptors, fermentation, substrate level phosphorylation. Additional catabolic pathways: lipid (fatty acid) catabolism, lipid hydrolysis = enzyme lipase will hydrolyze the bond between glycerol and fatty acid chains, glycerol is converted to dhap by phosphorylation and can enter the glycolysis pathway. Terminology of microbial control: biocides: chemicals that kill microorganisms on samples without specificity, disinfectant: physical or chemical agent that is used to inhibit or destroy microorganisms on inanimate objects, antiseptic: disinfectant that is used on skin. Temperature-based control: heat-related methods, effects of high temperature, proteins denature, structure and function of nucleic acids is disrupted.