PMY 302 Lecture 30: GI pharm
20 Dec 2018
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Document Summary
Reversible, competitive on the basolateral side of the parietal cells. Cimetidine (weak antiandrogenic effect: can cause gynecomastia) Nizatidine ignite a cascade event through camp to allow proton pump to release h+ Ecl releases histidine which will bind to the gs h2 receptor that will. Inhibits only active pumps so ingest before meal. Inhibit the final step of acid productions. Omeprazole: need to taper off because body will work harder. Misoprostol (-ol means prostaglandin) stomach by releasing bicarbonate. Just like how prostaglandins bind to epithelial cells to protect the. Sucralfate: al(oh)3 gel when hit the acid in the stomach becomes a gel to coat, no absorption, given before meals, avoid antacids, constipation is possible. Increase the oh to raise the ph above 4. When mg(oh)2 used itself can cause diarrhea.
