BIO 201 Lecture Notes - Lecture 22: Acetaldehyde, Electron Transport Chain, Aerobic Organism
11 Apr 2017
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Uncoupling h+ diffusion from atp synthesis: dnp a. i. Allows you to burn through glucose more quickly a. ii. Causes holes in the inner membrane of the mitochondria a. ii. 1. This causes the protons to leak back into the matrix and completely bypass atp synthase a. ii. 2. Glucose catabolism goes to nothing rather than making atp a. ii. 3. As a result, you end up with very low levels of atp a. ii. 3. a. This tells the cell you need to make more atp a. ii. 3. b. It then cranks up the activity of all of the enzymes in aerobic metabolism, which allows the cell to burn faster through all that glucose a. ii. 3. c. It takes everything it can and tries to push it into catabolism, but it fails a. ii. 4. However, people did not die from a lack of atp a. ii. 5. The movement of h+ down its gradient involves a transfer of energy (potential to mechanical to chemical) a. ii. 5. a.
