BIO 200 Lecture Notes - Lecture 12: Edward Tatum, George Beadle, Mendelian Inheritance
31 Oct 2017
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How do we reconcile the dna model with mendelian genetics: albinism= complete dominance, normal skin= aa or aa, albinos= aa. What determines the kind of protein made: a set of 3 nucleotide bases in dna (triplets) determines which amino acid will be used to put into the protein, (gga)ata(tcc)cct(tag)gga(agc)cct(tcg)aat( Cct: dna triplets, rna codeons go to protein. 4 cubed is 64: only need 20 different dna triplets and 20 rna codons, so those don"t work. Rna codons: several codons code for the same amino acid, ex. Phenylalanine is coded by uuu and uuc: leucine is coded by: uua uug cuu cuc cua cug, same messenger rna codons are used in virtually all organisms. What is a gene: a gene is a sequence of nucleotide bases that code for a polypeptide, example: (ctc)aaa(tgt)taa(aag)gtc(atg)gac(cgt)at . , the order of the nucleotide bases determines which amino acid is put into the polypeptide.
