BSC 469 Lecture Notes - Lecture 13: Mhc Class I, Polysaccharide, Apoptosis
13 Oct 2017
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Document Summary
Immune response to antigens: inflammation, response results in sequestering of the antigen, digestion (neutrophils) or phagocytose (macrophages, presentation of portion of antigen to immunocompetent lymphocytes. B cells maturation: b cells humoral production of antibodies (mark invading antigens for destruction by cells of the immune system, maturation takes place in the bone marrow. T cell maturation: t cell cell mediated response functions as cytotoxic cells or directs b-cell activity, t cell maturation takes place in the thymus. Thymus epithelioreticular cells: located at the boundary of the cortex and the capsule/trabecula. They act to isolate the developing t-lymphocytes from connective tissue. Located within the cortex; make compartments for the developing t cells; express mhci and mhcii; involved in t cell education. Located at the boundary between the cortex and the medulla; create functional barrier between cortex and medulla; express mhci and mhcii. Form the hassall"s corpuscles; unsure of function; keratinized; produce thymosin and thymopoietin.
