BIOL 1202 Chapter : Chapter 43 The Immune System
Document Summary
Concept 43. 1: in innate immunity, recognition and response rely on traits common to groups of pathogens. Skin is a barrier to microbes: continuously shed, removing microbes that gain a foothold on skin, many skin secretions contain natural antibiotics, give the skin a ph between 3-5, also has lysozyme. Mucus traps microbes entering the nose or mouth. Respiratory tract cilia sweep mucus and microbes away from lungs. Phagocytosis: ingestion of invading microorganisms by certain types of white blood cells. 4 types of phagocytic wbc"s: neutrophils, macrophages, eosinophil, dendritic cells. Toll-like receptor: bacteria: lipopolysaccharides: flagellin, viruses: cpg dna; dsrna. The leaking of fluid into the infected area causes the swelling. Nk cells: attacks body cells that are virally infected or cancerous, releases chemicals that initiate apoptosis (i. e. , cell death) Concept 43. 2: in adaptive immunity, lymphocyte receptors provide pathogen specific recognition. In mammals, we have the adaptive immunity that is slower but specific.
