BSC 431 Lecture Notes - Lecture 17: Serology, Metronidazole, Macrolide

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Campylobacter and helicobacter belong to the same rrna superfamily. Characterized by low g + c ratio, spiral gram negative rods, and microaerophilic growth requirements (cid:1) (cid:1) (cid:1) (cid:1) (cid:1) (cid:1) (cid:1) (cid:1) (cid:1) (cid:1) (cid:1) (cid:1) (cid:1) (cid:1: jejuni: poultry and humans. Major human enteric pathogen world wide: coli: pigs and humans, fetus: sheep, cattle, occasionally humans. Thin curved (comma shaped) gram negative rods to spirals. Become cocci when exposed to oxygen at high concentrations or upon prolonged culture. Slow growing, fastidious- unlike salmonella, shigella, and yersinia. Oxidase positive (cid:1) (cid:1) (cid:1) (cid:1) (cid:1) (cid:1) (cid:1) (cid:1) (cid:1) (cid:1) (cid:1) (cid:1) (cid:1) (cid:1) (cid:1) (cid:1) (cid:1) (cid:1) (cid:1: jejuni grows best at 42 c rather than 37 c. Zoonotic, with a variety of animals serving as reservoirs. The juice that always comes out of a package of raw chicken. Gets splashed on leafy greens for a salad, etc. Fever, cramping, abdominal pain, bloody diarrhea, vomiting possible.

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