BSC 300 Lecture Notes - Lecture 10: Flavin Adenine Dinucleotide, Reduction Potential, Intermembrane Space
Document Summary
Bsc 300 lecture 10- aerobic respiration and the mitochondrion ii. 2 step process: electron transport chain, flow of protons drives atp production. Energy for atp production provided by electrons in the carriers. About 3 atps per pair from nadh generated during tca. About 2 atps per pair shuttled from cytoplasmic nadh to mitochondrion using the glycerol-3-phospate shuttle (brain) About 3 atps per pair shuttled from cytoplasmic nadh to mitochondrion using the malate-aspartate shuttle (heart and liver) Strong oxidizing agents (like o2) have a high affinity for electrons. Strong reducing agents (like nadh) have a weak affinity for electrons. Redox reactions are accompanied by a decrease in free energy. Electrons are passed along the electron transport chain from one acceptor to another. These energy-releasing reactions are coupled to conformational changes in electron carriers. These changes move protons across the inner membrane into the intermembrane space. Electrons move through the inner membrane via a series of carriers of decreasing redox potential.