NSG 3301 Lecture Notes - Lecture 43: Adrenergic Receptor, Angiotensin, Adrenal Medulla
Document Summary
Two phases of cardiac cycle are systole and diastole. Blood pressure is measured in millimeters of mercury (mm hg) and is calculated by measuring the amount of blood leaving the hear multiplied by the amount of resistance in the peripheral vessels. Adrenergic receptors in the nervous system have role in blood pressure management. When alpha 1 receptors are stimulated they cause peripheral constriction and blood pressure increases. This effect, is similar to stimulation of sympathetic nerves, is called sympathomimetic effect. Alpha 2 receptors sites are located within the brain. Beta 1 receptor sites are located primarily in heart. Beta 2 receptor sites are located primarily in bronchial and vascular musculature. Renin, which is synthesized by the kidneys, produces angiotension i. Angiotension i is a basically inactive substance until it is converted to the active angiotensin ii. Is also stimulates secretion of aldosterone from the adrenal medulla. Hypertension is a chronic disorder for all age groups.
