BIOL 1001 Lecture Notes - Lecture 13: Homologous Chromosome, Sister Chromatids, Allosome

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cerisegiraffe538

15 Mar 2018

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Biol 1001 - lecture 13 - genetics & meiosis. Random alignment of homologous chromosomes during meiosis i. Either the maternal or paternal member of a homologous pair can end up at either pole of a cell. Homologues can go up or down in the previous figures. The chromosomes in a gamete are a mix of chromosomes from the two parents. Our gametes almost always contain both maternal and paternal chromosomes. During transition between prophase i and metaphase i, microtubules from spindle poles attach to kinetochores of chromosomes. Initial contacts between microtubules and chromosomes are random. Extremely important: allows mixing of maternal and paternal alleles of genes during meiosis i. Maternal and paternal genes are passed onto offspring via meiosis. As a result of microtubule alignment, the number of possible combinations of chromosomes in a gamete is . 2^n, or 2^23, or 8. 5 million combinations. For a cell with 8 chromosomes or 4 pairs, the haploid number is 4.

Related Questions

Which statements pertaining to genetic variability are correct? Check all that apply (note that wrong answers will be deducted from right answers)!

Crossing over is defined by the exchange of chromosome pieces during metaphase one of meiosis.

If a germ cell (i.e. parent cell before meiosis) had only two pairs of homologous chromosomes (i.e. 4 chromosomes total) there are 2 possible combinations of maternal and paternal chromosomes in gametes.

Siblings produced by sexual reproduction are different because sperms are different from one another and eggs are different from one another, and the combination of an egg and sperm is basically unique.

Random fertilization means that all possible combinations of eggs and sperm are equally likely, i.e. it is pure chance which sperm fuses with which egg.

Individual chromosomes contain thousands of genes. This means that during each crossing over event, more than one gene is exchanged between paternal and maternal chromosomes.

limedonkey586

1). Explain the significance of the fact that gametes contain half of the chromosome complement of somatic cells. Tell me something about variation, if you have a sibling (if you don't imagine you do) - how is your sibling's genetic make-up similar and/or different from yours? What about your mom and dad?

2). Explain the terms reductional division and equational division. What is reduced or kept equal? To which nuclear divisions do these terms refer?

3). What is the diploid number (2n = ?) of an organism if it has
a) 12 chromosomes at Anaphase of Mitosis?
b) 12 chromosomes at Anaphase I of Meiosis?
c) 12 chromosomes at Anaphase II of Meiosis?

4). Compare/contrast Metaphase I of Meiosis with Metaphase of Mitosis.

5). What are the two mechanisms of variation in Meiosis, and during which stage(s) does each occur?

6). Draw a diagram of a bivalent and label the following parts: centromere, sister chromatids, non-sister chromatids, homologous chromosomes, chiasma.

7). A diploid cell has 1 pair of acrocentric chromosomes (Chromosome 1) and 1 pair of submetacentric chromosomes (Chromosome 2).
Â· Gene X is on Chromosome 1. Gene Y is on the short arm of Chromosome 2 and Gene Z is on the long arm of Chromosome 2.
Â· The maternal chromosomes have the X, y, z alleles, whereas the paternal chromosomes have the x, Y, Z alleles.
Draw these chromosomes, labeling ALL alleles, as they might appear in Metaphase I of Meiosis.

-Complete the following sentences: metaphase of mitosis, prophase II of meiosis, crossing over, anaphase I of meiosis, variable, random fertilization, identical, random orientation, metaphase I of meiosis, prophase I of meiosis, metaphase II of meiosis, reduction division

Two processes that occur during meiosis produce genetically ____________ cells.

In a process called ____________ , paired homologous chromosomes align randomly at the cell equator. This occurs during this stage of cell division: ____________ .

In a process called ____________ , genetic material is exchanged between homologous chromosomes. This occurs during this stage of cell division: ____________ .

-Complete the following paragraph to describe nondisjunction and the resulting effects on chromosome number.

words: euploidy, primary nondisjunction, nomal, nondisjunction, secondary nondisjunction, homologous chromosomes, abnormal, trisomy, monosomy, sister chromatids, aneuploid

1.During meiosis I, ____________ separate and move towards opposite ends of the poles.

2.During meiosis II, ____________ separate and move towards opposite ends of the poles.

3.During meiosis I, if both members of a homologous pair go into the same daughter cell, ____________ is said to occur and no normal gametes are produced.

4.During meiosis II, if the sister chromatids fail to separate and both daughter chromosomes go into the same gamete, ____________ is said to occur. Half the gametes are aneuploid while the other half are euploid.

5.If an egg that contains 24 chromosomes instead of 23 chromosomes is fertilized by a normal sperm, ____________ is said to have occurred.

6.If an egg that contains 22 chromosomes instead of 23 chromosomes is fertilized by a normal sperm, ____________ is said to have occurred.

BIOL 1001 Lecture Notes - Lecture 13: Homologous Chromosome, Sister Chromatids, Allosome

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