BIO 203 Lecture 18: Lecture 18_ Respiratory Systems and Gas Exchange

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apricotmammoth292

18 Aug 2018

School

Stony Brook University

Department

Biology

Course

BIO 203

Professor

William Collins

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Document Summary

Each red blood cell is squeezing through a capillary has an opportunity for maximal exchange with the interstitial fluid - gas exchange. Gas exchange goes in both directions, occurs because of difference in pressures. Gas exchange only occurs in capillary beds (between alveolar space and plasma in the capillaries) Low oxygen content and high carbon dioxide content because cells are using oxygen and producing carbon dioxide through aerobic metabolism. O2 is not soluble in water/plasma - problem with getting oxygen in plasma. Co2 is great in dissolving in plasma. Water in plasma can hold a lot of carbon dioxide. Diffusion of o2 and co2 between lung and blood (or between blood and cells) obey fick"s law of diffusion. (cid:3046)(cid:3047) ds * (c2 - c1) thickness (ex. Ds: (diffusion coefficient) directly proportional to sa and inversely proportional to membrane. Things such as illness, disease, etc. can change diffusion coefficient (c2 - c1): (concentration gradient of gas) - driving force of diffusion.

Related Questions

True of False: Freshwater environments have a higher concentration of oxygen than saltwater environments.

QUESTION 2 If the difference in partial pressure of gas on either side of the barrier to diffusion is 0, which of these events will occur?

The area for gas exchange will increase to accommodate this similarity.

The constant for diffusion will decrease.

The rate of diffusion will be 0.

The distance thickness of the barrier to diffusion will also be 0.

QUESTION 3 On the x-axis of the oxygenâhemoglobin equilibrium curve is the partial pressure of oxygen in tissues. Which type of blood is most likely to be represented by the right-hand side of the axis? (Hint: the oxygen-hemoglobin equilibrium curve is figure 45.14 in your book on pg 913)

blood found in the left ventricle

blood found in the right atrium

blood found in the superior vena cava

blood found in the inferior vena cava

QUESTION 4 Which of these is an example of pulmonary circulation?

Blood is pumped from the right ventricle to the lungs.

Blood is pumped from the left ventricle to the aorta.

Blood is pumped from the aorta to the cardiac vein.

Blood is pumped from the inferior vena cava to the right atrium.

QUESTION 5 O2 will diffuse from blood to tissue faster in response to which of the following conditions?

an increase in the PO2 of the tissue

a decrease in the PO2 of the tissue

an increase in the thickness of the capillary wall

a decrease in the surface area of the capillary

QUESTION 6 Which of the following promotes oxygen release from hemoglobin?

a decrease in temperature

a decrease in carbon dioxide levels

a decrease in pH

a decrease in carbonic anhydrase

QUESTION 7 How does the medulla oblongata sense the amount of carbon dioxide in the blood?

A. Carbonic anhydrase produced by cells performing cellular respiration is exported and travels though the blood, and binds to a receptor on the medullary respiratory center, which causes a signal amplification resulting in a change in gene expression which results in the production of proteins that will cause the diaphragm to contract

B. CO2 produced by cells performing cellular respiration reacts with blood plasma for form an acid, which increases the pH of the blood, which causes the medullary respiratory center to contract the diaphragm

C. CO2 produced by cells performing cellular respiration reacts with blood plasma for form an acid, which decreases the pH of the blood, which causes the medullary respiratory center to contract the diaphragm

D. A and B

E. A and C

QUESTION 8 Which of the following parts of the lung are considered "dead space"? A. The alveoli B. The trachea C. The bronchi D. B and C E. All of the above

QUESTION 9 Which of the following blood vessels have the thinnest walls?

arteries

arterioles

capillaries

venules

veins

QUESTION 10 How does the interstitial fluid return to the bloodstream?

A. Interstitial fluid flows into the capillary where the osmotic pressure driving fluid into the bloodstream is greater than the blood pressure driving fluid out of the blood

B. Interstitial fluid flows into the capillary where the blood pressure driving fluid into the bloodstream is greater than the osmotic pressure driving fluid out of the blood

C. Interstitial fluid leaves the tissue via lymphatic ducts and travels through the lymphatic system, which returns the fluid to the veins. D. A and C

E. B and C

QUESTION 11 True or False: When an electrocardiogram (EKG or ECG) shows a flat line (aka asystole), medical personnel will restart the heart using a defibrillator.

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Background

Almost all animal and plant cells require oxygen and give off carbon dioxide. This is called gas exchange and it occurs by passive diffusion. Some animals do all or most of their gas exchange across their skin (for example amphibians) but they have very low metabolisms and use very little oxygen and get rid of very little carbon dioxide.

On the other hand humans (and other mammals) have very high metabolic requirements and we canât rely on gas exchange over the limited 1.5 to 2.0 square meters of our skin to get enough oxygen in and carbon dioxide out fast enough. Our gas exchange takes place across a very thin membrane in the Alveoli of the lung and the gas exchange surface in humans is estimated to be between 50 and 100 square meters, or between 25 and 67 times our skin surface area.

Our lungs provide a huge surface for gas exchange but they are a dead-end system. Once the oxygen in the lungs is used up it needs to be replenished and carbon dioxide builds up in the air spaces in the lungs and needs to get out. This is where the diaphragm and a few of the skeletal muscles become important. In its relaxed state the diaphragm is at its longest and the space in the thoracic cavity (and the lungs) is small. When the diaphragm contracts it shortens, which increases the volume of the thoracic cavity (and the lungs). The increase in size means the pressure is lower in the lungs than outside so air comes into the lungs (inhalation). As the diaphragm relaxes, the lungs decrease in size enough that the pressure inside the lungs is higher than the external air pressure so air comes out (exhalation).

Introduction

In this lab you will be building a model of a lung and experimenting with different ways to breath.

Supplies:

In the Lab Kit

One round 9" balloon (one lung, we donât need two for this)
medium-sized plastic bag large enough to fit over bottom end of bottle (diaphragm)
medium-size, thin rubber band

You supply

plastic 2-liter soda bottle with bottom cut off (thoracic cavity)

Tape (optional)

Directions:

1. Insert the balloon through the open bottom of a modified 2-liter soda bottle and up over the neck of the bottle. Pull the end of the balloon over the edges of the neck of the bottle. The balloon is held open by the neck of the bottle.

2. Place the plastic bag over the bottom (open) end of the 2-liter bottle and use the rubber band to hold it in place. This will serve as the diaphragm. To inflate the lung, blow into the balloon just before you fasten the rubber band. You can also wrap tape over the edges of the plastic bag to minimize air leaks

3. Grasp the bottom of the plastic bag and pull it down and push it up. Watch as the "lungs" (the balloon) expand and contract as you do this. The balloon has to change size because the air space between the balloon and bottle must remain constant. (Well, it would if the seal around the plastic bag and bottle were perfect).

You may block the "trachea" (the neck of the bottle) so that the air supply is cut off and watch as nothing happens when the "diaphragm" is pushed in and out.

This model isnât perfect. None of the joints are air tight as they would be in a real thoracic cavity. Pull the âdiaphragm down and watch the lungs expand . If you hold it in place, the lungs will collapse again over time. This is because of leaks and is not how real lungs work. Pushing the diaphragm in and pulling it out over and over does give you an idea of how lungs work. As the diaphragm tightens, contracts (pull down on the plastic bag) the lungs fill with air. As the diaphragm relaxes (push up on the plastic bag) air is expelled from the lungs .

There are several different ways we breath, i.e. expand our thoracic cavity so that our lungs can expand. You have just made a demonstration model of the diaphragm at work. You can also use your rib cage to expand and contract so that you can inhale and exhale. There are muscles between and around your ribcage which you can use to change the size of your thoracic cavity.

This is approximately what your model of a lung will look like.

Answer the questions on the Report Page

Report Page Name

1. Put a hand on your lower ribcage and try moving your ribs out and in. Does air also move in and out?

2. Someone with an upper back or neck injury may not have the options of using diaphragm or ribs to breath. They can learn to use the clavicle and the muscles attached to expand their thoracic cavity a small amount and breathe independently for short periods of time. Put your hand on you clavicle and try to raise and lower just that bone without using your diaphragm or your ribs. It isnât easy but you should be able to get a little air into and out of your lungs this way. How effective do you think this way of breathing is?

3. When you take a really deep breath you use all these muscle groups to help. Take a really deep breath and notice that your ribs expand, your lower abdomen comes out (a sign that the diaphragm has contracted) and your shoulders lift a little (the upper chest and clavicle are working). Now take a relaxed breath. Only your abdomen should go in and out. The movement of your abdomen is a result of the contracting diaphragm pushing on the contents of your âgutâ which forces your abdomen to push out.

Do you breath in or out when your diaphragm contracts?\

4. If a hole were poked in your thoracic wall (the wall of the pop bottle â the hole should be at least the diameter of a pencil)

a. what would happen when you tried to breath? (This is a pneumothorax).

b. Is the space between the balloon and plastic bottle still required to remain constant?

5. Would it be possible to live with a paralyzed diaphragm? Explain your answer.

fuchsiamuskrat152

Please help me answer this multiple choice questions: (please answer all questions)

No explantion needed just the answer needed.

physiology and neurobiology questions below.

31. Systemic arterioles dilate in response to _____.

A. Increased CO2 levels in the tissue

B. Decreased O2 levels in the tissue

C. Decreased pH in the tissues

D. All of the above

32. Blood in the pulmonary arteries ______

A. Contains hemoglobin which is about 98.5% saturated with oxygen

B. Has a PO2 of about 40 mmHg

C. Both of the above

D. Neither of the above

33. Completion of first meiotic division of oogenesis yields.

A. One secondary oocyte

B. Four primary oocyte

C. Four mature ova (egg cells)

D. Four secondary oocytes

34. The final absorbable products of chemical digestion occurring in the brush border of the small

intestine include:

A. Monosaccharides and amino acids

B. Proteins and chylomicrons

C. Disaccharides and amino acids

D. Monosaccharides and disaccharides

35. The hemoglobin oxygen curve saturation curve plots ____ on the dependent (Y) axis and ____

on the independent (X) axis.

A. Oxygen concentration; hemoglobin concentration

B. % oxygen saturation of hemoglobin; PO2 of blood

C. % oxygen saturation of hemoglobin; PCO2 of blood

D. Hemoglobin concentration; oxygen concentration

36. In contrast to the female hypothalamic pituitary-sex steroid axis, control of the male axis is

aimed at ____.

A. Allowing spermatogenesis to occur just once a month

B. Keeping levels of pituitary gonadotropins relatively constant in blood

C. Keeping levels of hypothalamic releasing hormones higher than usual in blood

D. Causing a positive feedback effect of sex steroid up on gonadotropins

37. Which of the following will correct acidosis?

A. Speed up the proton pump

B. Buffering of protons with phosphate in the tubular lumen

C. Renal metabolism of glutamine

D. All of the above

38. Epithelium with a brush border (microvilli) is characteristics of the mucosa found in

A. Duodenum

B. Proximal Tubule

C. Both of the above

D. Neither of the above

39. The transport maximum (Tm) for glucose, addition filtered glucose

A. Is no longer filtered

B. Appears in urine

C. Is secreted

D. Is reabsorbed

40. Stroke volume is equal to ____.

A. End-diastolic volume alone

B. End-diastolic volume plus end-systolic volume

C. Cardiac output minus heart rate

D. End-diastolic volume minus end-systolic volume

41. The long term solution to a change in blood pH involves

A. Digestive System

B. Respiratory System

C. Buffers such as hemoglobin

D. Renal System

42. The left heart receives blood from ___ and pumps blood out through the ____.

A. Superior vena cava; pulmonary trunk

B. Pulmonary veins, pulmonary trunk

C. Pulmonary veins; aorta

D. Pulmonary arteries; aorta

43. Selection and activation of specific B lymphocytes may lead to all EXCEPT_____.

A. Formation of memory cells

B. Secretions of antibodies

C. Activation of complements to destroy tagged antigen

D. Secretion of perforin

44. Bile is stored and released into the duodenum from the

A. Liver

B. Pancreas

C. Gall Bladder

D. Duodenum

45. Beta oxidation of fatty acids yields _____,which then can be further oxidized to produces ATP.

A. Glycogen

B. Amino acids

C. Keto acids

D. Acetyl CoA

46. The relationship between the loop of Henle and the vasa recta capillaries function.

A. Absorption of glucose, amino acids and creatinine

B. Countercurrent exchange

C. Countercurrent multiplication

D. All of the above

47. Anterior pituitary production of Follicle Stimulating Hormone (FSH) is decreased by

A. Testosterone from Sertoli cells

B. Inhibin from Sertoli cells

C. Inhibin from interstitial (Leydig) cells

D. Luteinizing Hormone (LH) from granulosa cells

48. A response to acidosis would involve

A. Slowing down the proton pump

B. Greatly increased excretion of HCO3- (bicarbonate ions)

C. Both of the above

D. Neither of the above

49. The conversion of spermatid to spermatozoa occurs

A. By differentiation process in the seminiferous tubule

B. In epididymis

C. By meiosis, in the seminiferous tubule

D. In the prostate gland

50. Antibody-mediated immunity defends against ____.

A. Virus infected cells

B. Viruses and bacteria in the blood or body fluids

C. Bacteria only

D. Viruses only

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BIO 203 Lecture 18: Lecture 18_ Respiratory Systems and Gas Exchange

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