EXSC 224 Lecture Notes - Lecture 5: Medulla Oblongata, Neural Tube, Epithalamus
Document Summary
G protein-linked receptors - second messenger systems. Sits next to the membrane, inside the cell. Activation of g protein causes events, that activates a second messenger, which opens a channel. These cause formation of an intracellular second messenger (cyclic amp in this case) that brings about the cell"s response. When neurotransmitter binds to a receptor, the receptor changes shape. G protein gets its name from gtp. Gtp can be used as an energy source. This is what powers the g protein. This causes g protein it to move. Adenylate cyclase is an enzyme that uses atp. Causes the molecule to form a circle. Adenylate cyclase converts atp to camp (2nd messenger) Camp stimulates things to happen inside the cell. 5a. camp changes membrane permeability by opening or closing ion channels. Forward the processed information to other destinations. One presynaptic fiber synapses onto several post synaptic fiber. Single presynaptic fiber ranches and synapses with several neurons in the pool.
