EXSC 224 Lecture Notes - Lecture 4: Axon Hillock, Muscarine, Endorphins
Document Summary
Time the neurotransmitter is in the area. Depolarizing stimulus - membrane potential rises toward 0. Kind of signal that leads to action potential if large enough. Neurotransmitter binds to and opens chemically gated channels that allow simultaneous flow of na and k+ in opposite directions. Na+ influx is greater than than k+ efflux, causing a net depolarization. Epsp helps trigger ap at axon hillock if epsp is of threshold strength and opens the voltage-gated channels. Make it more difficult to excite a neuron. Neurotransmitter binds to and opens channels for k+ or cl- Causes a hyperpolarization (the inner surface of membrane becomes more negative) Reduces the postsynaptic neuron"s ability to produce an action potential. Add and adhd - associated with inactive regions of the brain. This region of the brain inhibits other regions of the brain, making it difficult to focus. Stimulant (riddalin) excites this region of the brain.
