BIO 212 Lecture Notes - Summer 2018 Lecture 4 - Vasodilation, Cardiac output, Starling equation

• School: Saint Vincent College
• Department: Biology
• Course: BIO 212
• Professor: Dr Retna

Document Summary

Cardio vascular system: the cardiovascular system is composed of the heart and blood vessels. The action potential in the atria and ventricles exhibits a plateau: plateau is the result of an inward ca2+ current. In myocardial cells, however, ca2+ entering the cell during the plateau of the action potential serves as a trigger for the release of more ca2+ from the sarcoplasmic reticulum. Ca2+ then binds to troponin c to allow cross-bridge formation. The frank-starling law of the heart describes this relationship between cardiac output and end-diastolic volume: end-diastolic volume reflects venous return. Therefore, cardiac output is determined by venous return, and in the steady state, cardiac output and venous return are equal: pa is the product of cardiac output and tpr. Pa back to normal: the renin angiotensin ii aldosterone system is a slower, hormonal mechanism that detects changes in pa and, via aldosterone, restores.