01:146:328 Lecture Notes - Lecture 12: Sputum, Macrophage, Pleurisy

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Species belonging to 8 genera, representing 5 families, commonly infect various visceral organs of human. Several member so paragonimus, notable p. westermani live in the lungs. Can be distinguished from other digeneans by its highly branched testes and caeca. Adult worms live in the bile ducts, gall bladder, and liver tissue of host: life cycle: the eggs are relatively large, operculate, and yellowish brown in color. They"re expelled before the miracidium is fully developed, pass into host alimentary tract vis bile duct, and eventually reach exterior with feces where they must reach fresh water to continue cycle. The miracidium has eyespots and is positively phototaxic. They must find a snail host (lymnaea, succinea, fossaria, practicolella serve as 1st intermediate host). Upon penetration each miracidium metamorphoses into a sporocyst > rediae > cercariae > metacercariae (on plants where sheep and cattle feed). Humans become infected when eating contaminated watercress and other vegetation.

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