01:146:328 Lecture Notes - Lecture 5: Opisthorchis Viverrini, Fasciola Hepatica, Clonorchis Sinensis
1 Oct 2018
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1: ingestion of food, foodborne trematode infections, foodborne diseases. Opisthorchis viverrini: life cycle and diagnosis, pathology - liver fluke induced malignancies. Fasciola hepatica: sheep liver fluke, life cycle, digestive tract, pathology, paragonimus westermani, life cycle, pathology, diagnosis. Treatment of trematode infections: praziquantel, fasciola hepatica. Control of trematode infections: eliminate adult worms, no night soil, snail control, fasciola hepatica, clonorchis sinensis and opisthorchis viverrini, paragonimus westermani, control reservoir hosts. Food contaminated with larval stage of parasite. Human enters the life cycle and replaces the natural definitive host. Liver duct causing damage to the lining. Life cycle and diagnosis are very similar: sinensis branched testes, viverrini lobed testes. 100 1000 worms nausea, diarrhea, pain. 1000 or more worms fever, pain, jaundice, thickening & block of bile duct. Give some examples of infections which cause cancer in humans. Mechanical injury from oral and ventral suckers attaching to biliary. Lesions, ulcerated fluke eggs become trapped in ulcers.
