01:119:116 Lecture Notes - Lecture 26: Thymus, Adaptive Immune System, Histocompatibility

• School: Rutgers University
• Department: Biological Science
• Course: 01:119:116
• Professor: Daniel Stern Cardinale

Document Summary

We are going to focus on adaptive immunity. 1. it takes several days to mobilize adaptive immunity: adaptive immunity are the specific defenses, until then, the innate defenses are what will destroy the pathogens, lymphocytes (wbcs) they function in innate and adaptive immunity. B cells: b cells have y-shaped receptors cell. 2. these receptors consists of 4 polypeptide chains. T cells (part of specific immune response so they will bind to a specific antigen: t cell antigen receptors bind only to fragments of antigen displayed on the surface of a host cell. 1. these host cells are characterized by major histocompatibility complex (mhc) molecules: mhc are host proteins that display antigen fragment on cell, antigen receptor surface, consists of 2 different polypeptide chains. 2. there is an alpha chain and a beta chain they are linked by disulfide bridges. 4. there is a transmembrane region: acts as an anchor.