01:119:116 Lecture Notes - Lecture 28: 1918 Flu Pandemic, Influenza A Virus Subtype H2N2, Herd Immunity
12 Jun 2017
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Pathogen = an organism that causes a disease. A. c)intrinsic factors = what your body does in response to illness (a. c. 1) Extrinsic response = things pathogen is actually doing (a. d. 1) Ex. tissue damage, poison that pathogen gives off and makes you sick. Spanish flu, asian flu: types of pathogens. Live attenuated: weakened infectious organisms (a. d. 1. i)polio (sabin vaccine), yellow fever, smallpox (a. d. 2) Inactivated: killed-inactivates (a. d. 2. i)polio (salk vaccine) pertussis, rabies (a. d. 3) Subunit: small part of pathogen (a. d. 3. i)influenza type b (a. d. 4) Dna: injection with genetically engineered dna that produce an antigen (veterinary use only at present) A. e)herd immunity: if most of population is vaccinated, unvaccinated individuals will not get the disease (a. e. 1) Not everyone can get vaccines for various reasons, so if most people are vaccinated, even the people that are not vaccinated can be safe. A. f) why are there new flu vaccines every year? (a. f. 1) Antigenic drift: small changes in viral antigens due to mutation (a. f. 2)
