01:119:116 Lecture Notes - Lecture 28: Rheumatoid Arthritis, Meiosis, Apicomplexan Life Cycle

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Intrinsic factors what your body does in response to illness. Virulence - the ability to cause disease. Pathogen - an organism that cause a disease. Extrinsic factors pathogen caused tissue damage. Asian flu (h2n2) 1957: types of pathogens. A variant or derivative of a pathogen. Would cut an infected person"s smallpox and put it on a small cut to another person"s body to help make the antibodies. There"s a chance they can catch the disease. Ex: polio (sabin vaccine), yellow fever, smallpox. Dna - injection with genetically engineered dna that produce an antigen (veterinary use. Ex: influenza type b only at present) Herd immunity: if most of population is vaccinated, unvaccinated individuals will not get the disease. Antigenic drift - small changes in viral antigens due to mutation. Antigenic shift - major changes in viral antigens due to viral reassortment or recombination. Change in protein"s shape = change in function! Strain replacement - less common strain replaces a common one.

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