01:119:115 Lecture Notes - Lecture 6: Phagocytosis, Fokker E.Ii, Lysosome
27 Sep 2016
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Form bilayer a. iv. 2. b/c cylindrical shape a. iv. 2. a. a. iv. 2. b. very strongly amphipathic i. a. iv. 2. b. i. one portion polar, other end non polar a. iv. 2. b. a. iv. 2. b. ii. bilayer held together mainly by hydrophobic interactions a. iv. 2. b. iii. hydrophobic interactions a. iv. 2. b. iv. Degree of fatty acid saturation a. iv. 2. c. ii. 3. a. more fluidity a. iv. 2. c. ii. 4. Associates with inner portion with membrane - also hydrophobic a. iv. 2. c. ii. 4. c. ii. Prevents membrane from solidifying at low temp. a. iv. 2. c. iii. 1. a. iii. Interacts strongly with head region of phospholipid a. iv. 2. c. iii. 1. a. iv. Evolution of differences in membrane fluidity p. 127: mosaic (part of fluid mosaic model) b. i. Proteins determine most of functions of the membrane b. i. 1. Deeply inserted into the membrane b. i. 2. a. ii. may even span the membrane then called transmembrane b. i. 2. a. iii. have internal hydrophobic regions b. i. 2. a. iv. act as spacers effect of fluidity b. i. 2. a. v. Not embedded but associated w/ membrane b. i. 2. b. ii. Some proteins are going to be held in place by cytoskeleton b. i. 2. b. iv. 1. Can move laterally within a single layer of the membrane b. i. 2. b. v. 3.
