NROSCI 0081 Lecture Notes - Lecture 18: Low-Density Lipoprotein, Helicobacter Pylori, Circulatory System
Document Summary
Belongs to family of drugs known as methlyxanthines. Properties discovered between 12th and 15th century. The bean is the seed inside of a berry or other plants. Made from the leaves of camellia sinensis. The highest caffeine is in the bud and first two leaves closest to the bud. The average american drinks 3. 1 cups of coffee each day. Completely absorbed from stomach and small intestine (does not take long) Almost all of it absorbed within 30 min. Peak blood levels occur within 15-120 min. Nicotine decreases life by up to 50% Where caffeine does most of its work, where the buzz comes from. In the brain it is a neuromodulator (binds metabotropic receptors) Gaba is inhibitory transmitter with depressant effects; anti-anxiety and pain relieving. Only occurs at high and dangerous levels. Requires a ton of caffeine to do this! Raphe nuclei and locus coeruleus: sleep and mood (serotonin and ne)
