BIOS 1700 Lecture Notes - Lecture 22: Dynein, Spindle Apparatus, Tubulin

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Monomers: alpha tubulin and beta tubulin: forms a straw-like structure, always associates with the centrosome at the minus end of the microtubule. Minus end is always close to the cell nucleus: looks like a spider-web or bike spokes. Forms spindle apparatus during cell division: cellular movement with microtubules. Contain motor proteins, atp and atpase: kinesin. Moves from the end to the + end: uses atp and atpase to move. Looks like it crawls along the microtubule: dynein. Moves from the + end to the end: uses atp and atpase to move. Mostly moves pigments, vesicles and proteins throughout the cell: zebra fish. This is a form of camou age defense. Cilia and flagella: form ordered structures to support, dynein holds microtubules together, dynein allows microtubules to sway or move. Dynein holds microtubules at a set distance apart, so when dynein moves up or down the microtubule it causes the microtubule to bend.