EEOB 2520 Lecture Notes - Lecture 28: Neural Development, Kolmogorov Space, Anterior Pituitary

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Thyroid hormones: t4 most abundant, t3 most active, more effective. Chemical difference between them is 1 iodine t4 has 4 and t3 has 3. They are nonpolar and being transported through a polar substance could get injured. If we have t4 and it travels and gets injured = will become t3. If we have t3 and it travels and gets injured = will become t2: what will t2 do for us in our system = nothing. So it is safer to have more t4 in the system because it will transport better and more easily, and if we injure it, we will get t3 which is more effective and better anyway. Most of our cells have the capacity to take 1 iodine off of t4 and turn it into t3: if it is not injured during transport, the cell can make it t3 which is most effective anyway.

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