BIOS 10161 Lecture Notes - Lecture 21: Electrochemical Gradient, Uncoupling Protein, Atp Synthase
18 Nov 2016
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How does oxidative phosphorylation form atp: oxidative phosphorylation: atp is synthesized by reoxidation of electron carriers (nadh and fadh2) in the presence of o2, **this is where the bulk of the atp comes from** Electrons from nadh and fadh2 pass through the respiratory chain of membrane associated carriers. Electrons flow results in a proton concentration gradient in mitochondria. Potential energy for work to be performed in the cell. This produces too much energy like lighting dynamite in the cell: cell would not be able to harvest the energy. Need to do it gradually in series of reactions: then can be captures by an endergonic rxn. Energy is released as electrons are passed between carriers. Ex: protein complexes i iv, cytochrome c, and ubiquinone (q) Mitochondria folded (cristae) to increase sa for reaction. Proton gradient also establishes a ph gradient. During et, protons are also actively transported.
