BIOL 1201 Lecture : Ch17 Lecture Presentation Rev Spr 14
Document Summary
Cindy s. malone, phd, california state university northridge. Information in genes directs the synthesis of rnas and proteins by looking at then asking. A cell builds the proteins it needs. According to the central dogma of molecular biology. The first step in converting genetic information into proteins is transcription. Synthesis of an mrna version of the instructions stored in dna. Rna polymerase performs this synthesis by transcribing only one strand of dna. The other dna strand is called the non-template, or coding strand. Except that rna has uracil (u) in place of thymine (t) An rna polymerase performs a template-directed synthesis in the 5 -to-3 direction. Rna polymerases do not require a primer to begin transcription. Initiation is the first phase of transcription. Rna polymerase cannot initiate transcription on its own. Sigma and rna polymerase together to form a holoenzyme. An enzyme made up of a core enzyme. Made up of the core enzyme and a sigma subunit.
