BISC 260 Lecture Notes - Lecture 14: Adenylyl Cyclase, Ribosomal Rna, Cyclic Adenosine Monophosphate
1 Nov 2016
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Document Summary
Two approaches to regulation, regulation of gene expression, transcription initiation, transcription elongation, translation, alter activity of enzymes and proteins, posttranslational, three domains of life differ in genome structure and regulatory mechanisms used. Negative control means binding to the gene turns it off. Corepressor must be present to bind with the repressor protein which in turn binds to operator sequence in the dna. When activator + inducer bind; the complex binds to. Dna, recruiting rna polymerase to the gene or operon: positive control of a repressible gene, gene is on when activator protein is bound. Gene is turned off in the presences of the inhibitor and activator protein because it inhibits the activator"s ability to bind to the dna. The tryptophan (trp) operon: consists of 5 structural genes which code for enzymes needed to synthesize tryptophan, negative transcriptional control of repressible genes by trp repressor, operon only functions in the absence of tryptophan.
