BSCI 10001 Lecture Notes - Lecture 22: Stop Codon, Dna Repair, Release Factor

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emmagennaro

28 Apr 2019

School

Kent State University

Department

Biological Sciences

Course

BSCI 10001

Professor

Adam Arthur Leff

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Document Summary

Overview: the small and large subunits join each other near the 5" end of an mrna molecule. The ribosome then runs down the length of the mrna, translating it (in conjunction with trna molecules) into the protein which it encodes. After finishing its run along the length of an mrna molecule, the two subunits dissociate and release from the mrna. In the picture shown, many amino acids have already been polymerized, and a (correct) gly-trna is coming into the a site. When the gly bonds with the phe in the p site, that will simultaneously break the phe-trna bond. Here"s how your text represents the figure shown in the preceding slide. Let"s look at the way your text presents all this. Here is a more chemically detailed depiction of the way a second amino acid (attached to its trna) becomes attached to the growing polypeptide chain.

Related Questions

31. T or F. In pre-mRNA splicing, the 5â splice site, 3â splice site, and the cleavage site in the
intron sequence each have a consensus nucleotide sequence.
32. T or F. The addition of an amino acid to a tRNA molecule is an example of a molecular
switch.
33. T or F. The binding of a ligand to its specific plasma membrane receptor is an example
of a molecular switch.
34. T or F. Energy obtained from ATP hydrolysis is used to attach each amino acid to its
tRNA molecule in a high energy bond that is used later in the ribosome to join an amino
acid into the polypeptide chain.
35. T or F. Every new protein, as it emerges from RNA polymerase in the nucleus, is
comprised of amino acids that have been joined together in a linear chain.
36. T or F. The ribosome has a total of 3 RNA binding sites, including the A, P, and E sites.

Question 9

Codominance is a form of inheritance in which two different allelesfor a gene are both expressed, and neither allele is dominant overthe other. One example of codominance is fur color in cattle; thealleles for red fur and white fur are codominant. If a homozygousred cow and a homozygous white bull mate, what would you expect tofind in their offspring?.912.l.16.2>

They will all have white fur.

Their fur will be a mixture of red and white hairs.

Their fur will be a lighter shade of red.

They will all have red fur.

Question 10

If a tRNA molecule has an anticodon which reads AUG, what will itmatch up with and what amino acid is it carrying?
.912.l.16.5>

	U		C		A		G
	UUU	Phenylalanine	UCU	Serine	UAU	Tyrosine	UGU	Cysteine	U
U	UUC	Phenylalanine	UCC	Serine	UAC	Tyrosine	UGC	Cysteine	C
	UUA	Leucine	UCA	Serine	UAA	Stop	UGA	Stop	A
	UUG	Leucine	UCG	Serine	UAG	Stop	UGG	Tryptophan	G
	CUU	Leucine	CCU	Proline	CAU	Hisitidine	CGU	Arginine	U
C	CUC	Leucine	CCC	Proline	CAC	Hisitidine	CGC	Arginine	C
	CUA	Leucine	CCA	Proline	CAA	Glutamine	CGA	Arginine	A
	CUG	Leucine	CCG	Proline	CAG	Glutamine	CGG	Arginine	G
	AUU	Isoleucine	ACU	Threonine	AAU	Asparagine	AGU	Serine	U
A	AUC	Isoleucine	ACC	Threonine	AAC	Asparagine	AGC	Serine	C
	AUA	Isoleucine	ACA	Threonine	AAA	Lysine	AGA	Arginine	A
	AUG	Methionine/Start	ACG	Threonine	AAG	Lysine	AGG	Arginine	G
	GUU	Valine	GCU	Alanine	GAU	Aspartate	GGU	Glycine	U
G	GUC	Valine	GCC	Alanine	GAC	Aspartate	GGC	Glycine	C
	GUA	Valine	GCA	Alanine	GAA	Glutamate	GGA	Glycine	A
	GUG	Valine	GCG	Alanine	GAG	Glutamate	GGG	Glycine	G

It is carrying arginine and will match with a CGU codon on themRNA.

It is carrying methionine and will match with a TAC codon on theDNA.

It is carrying methionine and will match with a UAC codon on themRNA.

It is carrying tyrosine and will match with a UAC codon on themRNA.

Question 11

While the DNA in a human skin cell was being replicated, a singlebase was miscopied. What will be the most likely result of this forthe cell in which it happened?.912.l.16.3>

All the proteins the cell creates from the miscopied strand willdo different jobs than the old ones.

If the new sequence codes for the same amino acid as theoriginal cell, it will function normally.

Both new DNA strands will end up together in a new cell, and theinaccurate one will be discarded.

Any miscopied DNA will be replaced with an accurate DNA copyonce the cell divides.

Question 12

A ferret's haploid number of chromosomes is 20. How would thenumber of chromosomes in the ferret's body cells compare to thenumber of chromosomes in its gametes?.912.l.16.17>

Its body cells would have 20 chromosomes, and its gametes wouldhave 40 chromosomes.

Its body cells and gametes would both have 40 chromosomes.

Its body cells and gametes would both have 20 chromosomes.

Its body cells would have 40 chromosomes, and its gametes wouldhave 20 chromosomes.

Question 13

A body cell is in the longest stage of its life cycle. The cellgrows, synthesizing proteins and increasing in size. Eventually,the cell will grow too large to carry out normal activities. Whichof the following is the best conclusion you can make about the lifecycle of this cell?.912.l.16.14>

The cell is close to the end of its life cycle, and a chemicalsignal will initiate cell death.

The cell is ready to undergo mitosis, and a chemical signal willsend the cell to prophase.

The cell is in the G1 phase of interphase, and a chemical signalwill send the cell to the S phase.

The cell is in the S phase of interphase, and a chemical signalwill move the cell to the G2 phase.

Question 14

While mRNA strands are being created a sequence is sometimesmiscopied. What is the best possible outcome for the cell shouldthis take place?.912.l.16.5>

The miscopied sequence codes for the same amino acids as theoriginal sequence.

The new sequence creates a protein that serves a differentfunction from the original.

The ribosomes will correct the mistake before the tRNA matchesan amino acid to it.

The mRNA will only be used to create non-critical proteins forthe cell.

Question 15

Over the last several decades, the scientific community hasgathered a large amount of information regarding genetics andgenetic variation. What are two main sources that lead toincreased genetic variation?.912.l.15.15>

Selective breeding

Gamete mutations

Recombination

Genetic drift

salmonlouse680

Which of the two major categories of the chemical reactions in photosynthesis is oxygen the INDIRECT product?

Glycolysis

Oxidative phosphorylation

Both light and dark

Light independent phase (LIP)

Light dependent phase (LDP)

You have a stomach flu characterized by vomiting. Which of the following systems is most responsible for the food in your stomach going the wrong way, e.g. vomiting? (Disregard this question and answer choice B)

Cardiac Muscle in the large intestine as discussed in class.

Smooth muscle in the gastrointestinal tract

Smooth muscle in the blood vessels

Skeletal muscle in the intestine

Proteins are made from which of the following smaller sub units?

Nucleotides

Amino acids that cannot enter the blood stream and go to cells

Monosaccharides

Fatty acids

Amino acids which can form new protein

Carbohydrates are digested in the gastrointestinal system into which of the following substances that is the smallest structure?

Polysaccharides that are produced by glucagon

Monosaccharides that are produced by insulin

Monosaccharides

Polysaccharide

Which of the following biomolecules has the longest digestion time? In other words, how long does it take for the biomolecule to be catabolized?

DNA

Lipid

Carbohydrate

Protein

You are sunburned after a long day at the beach. Which one is not an example of UV damage to your skin cells?

A mutation can occur in your ovaries

A mutation can occur in skin cell DNA that can lead to errors in transcription.

Errors can occur during DNA replication.

UV light can cause mutations in DNA of skins cells.

Thymine bases in your skin DNA bond with each other instead of across the double helix

This region, the ______________ (a) tells RNA polymerase where to bind to DNA while this region, the ______________ (b) tells RNA where to start transcription.

(a) promoter, (b) open reading frame

(a) start codon, (b) methionine

(a) promoter, (b) start site

(a) start site, (b) promoter

The genetic code is used to translate ______________ into ______________.

lipids, nucleotides

nucleotides,carbohydrates

nucleotides, lipids

nucleotides, amino acids

nucleosides, amino acids

Transcription of a gene has just completed. What are the next steps (in the correct order) to complete expression of that gene?

RNA polymerase makes a copy of DNA into mRNA.

mRNA is translated in the nucleus and ribosomal RNA moves into the cytoplasm.

Gene expression is completed after transcription.

mRNA moves into the cytoplasm and with tRNA they interact to form protein

Translation machinery moves into the nucleus and mRNA is translated into protein.

How is it that a mutation in DNA stored inside the nucleus of a cell can cause a disease affecting multiple organs?

This remains an unanswered question in science that scientists are still trying to figure out.

The mutated DNA is expressed in multiple cells through the process of transcription and translation, and the altered protein causes the disease wherever the DNA was expressed.

The mutated DNA is expressed in one cell and the altered protein travels to multiple organs to cause disease.

The mutated DNA is expressed and the mRNA takes the mutated information to other cells where the altered protein is made to cause disease in that organ.

The advantage of sickle cell anemia is which of the following?

It decreases the amount of oxygen in the blood cells so that mosquitoes carrying malaria will live

It decreases the amount of oxygen in the blood cells so that mosquitoe's blood form will die.

It allows the blood vessels to decrease the amount of blood going to the toes and feet.

There is none.

Which of the following is a purpose of cell division?

Cell reproduction

Growth

Repair

All of these

BSCI 10001 Lecture Notes - Lecture 22: Stop Codon, Dna Repair, Release Factor

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