BIO 12D Lecture Notes - Lecture 32: Fallopian Tube, Seminal Vesicle, Bulbourethral Gland
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Based on âMorgan: A case of Diabetesâ by Lisa Rubin and Clyde Freeman Herreid (National Center for Case Study Teaching in Science)
The Patient:
Morgan Water is a 27-year old Native American that lives on a reservation in Oklahoma. Nearly ¼ of Morganâs tribe has diabetes but she has no direct family history of diabetes, heart disease, or other serious conditions. She is however obese (BMI = 32) and leads a sedentary lifestyle. Morgan has been suffering from an increasing persistence of symptoms including unusual thirst, dizziness, blurred vision, and numbness in her right foot. The symptoms have been developing over several months but as she is planning her wedding she attributed them to nerves. She is finally persuaded to see her family doctor. Her non-fasting blood glucose level was elevated so the doctor has her return the next morning for a fasting blood sample so they could more accurately measure her blood glucose and insulin. Her blood results are below:
Test | Morganâs values | Normal range | Pre-Diabetic range | Diabetic range |
Plasma glucose, mg/dl | 260 | 70 -139 | 140 - 199 | ⥠200 |
Fasting glucose, mg/dl | 140 | ⤠99 | 100 - 125 | ⥠126 |
A1C, % | 7.6 | ~ 5 | 5.7 â 6.4 | ⥠6.5 |
Fasting Insulin, mIU/ml | 34 | 2 - 10 | 10 - 20 | ⥠20 |
Question 1:
Based on her history and blood results, what do you think is the most likely diagnosis for Morgan?
A. Type I Diabetes Mellitus
B. Type II Diabetes Mellitus
C. Pre-Diabetes
D. Cardiovascular Disease
Question 2:
What is the cause of Morganâs disease?
A. It is an auto-immune disorder that destroys the β-cells of her pancreas so she produces less
insulin than normal.
B. She has a genetic mutation that results in less insulin receptor being produced than normal.
C. She has developed insulin resistance, where her insulin receptors do not recognize the insulin her
body produces, likely due to her obesity.
D. There is no known cause, it can happen spontaneously.
Morgan is worried that she will have to spend the rest of her life giving herself injections but her doctor does not prescribe insulin injections.
Question 3:
Why would injections of insulin not help Morgan if she has hyperglycemia?
A. Her body is already producing excess insulin but not responding to it.
B. Her problem is with her insulin receptors responding to insulin.
C. Excess insulin will only exacerbate her insulin resistance.
D. All of the above.
Question 4:
Given Morganâs metabolic state, which of the following pathways would you expect to be active in Morganâs cells (select all that apply)?
A. Glycolysis
B. Gluconeogenesis
C. β-oxidation
D. Amino acid degradation
E. Protein synthesis
Please help me check my answers and correct them if needed.Thank you!
1. Which statement regarding malnutrition is true?
Malnutrition of one nutrient may directly and indirectly affectonly one system | |
All nutrient deficiencies typically manifest in a matter of daysor weeks. | |
Most cases of malnutrition in the elderly are directly relatedto a loss of appetite | |
Nutritional homeostasis should primarily be achieved bydietary alterations. |
2. Movement of the stomach/stomach lining upward into esophagusor diaphragm is termed what?
Gastric reflux | |
Gastric torsion | |
Hiatal hernia |
3. Which of the following is a function of the liver?
produce and secrete insulin | |
produce and secrete glucagon | |
metabolize drugs | |
excrete drugs from the body | |
store red blood cells |
4.
Which of the following regarding malnutrition is true?
ingestion of supplements will prevent malnutrition | |
malnutrition can be avoided if the recommendations of the foodpyramid are followed | |
malnutrition in the United States is rare |
5. What is protein-carbohydrate malnutrition? A person who:
doesn't eat enough protein or carbohydrates | |
eats to much protein and not enough carbohydrates | |
eats to much carbohydrates and not enough protein | |
eats to much protein and carbohydrates which interferes withabsorption and digestion of other nutrients |
6. Which vitamin is stored in the tissues?
A | |
B | |
C |
7. The menstrual occurs within 3 or 4 days of which of thefollowing changes in the blood?
increase in estrogen and decrease in progesterone | |
increase in progesterone and decrease in estrogen | |
increase in progesterone and estrogen | |
decrease in progesterone and estrogen |
8. Which statement regarding sperm production and aging istrue?
Aging increases the amount of sperm produced | |
Aging has a variable effect on the amount of spermproduced. | |
Aging causes major changes in sperm cell morphology | |
Aging causes major changes in sperm cell function |
9. Which of the following is a function of the digestivesystem?
Helping with speech | |
Vitamin A production | |
Storing blood in the pancreas | |
Producing erythropoietin |
10. Thinning of the enamel, decrease in nerve cells, recedinggums and loss of muscle of mastication coordination are consideredto be what type of changes in the mouth?
Abnormal changes | |
Age changes |
11. A decline in sexual activity with age is primarilyassociated with what age related changes in the physiology of amale?
Decline in frequency of use | |
Deteriorating self-image | |
Medication use | |
Changes in blood flow |
12. Which of the following conditions is not apathological change that effects the stomach?
Peptic ulcer | |
Atrophic Gastritis | |
Acute Gastritis | |
Stricture |
13. Which of the following is an age related cause for fecalincontinence?
Laxative use | |
Ulcerative colitis | |
Colorectal cancer | |
Disability | |
Stool softener |
14. A decrease in lactase secretion is an age related changeassociated with the _____________.
stomach | |
small intestine | |
large intestine | |
pancreas |
15. Which of the following statements regarding atrophicgastritis is true?
causes overproduction of HCL | |
causes overproduction of intrinsic factor | |
increase absorption of B12 | |
increase risk for cancer |
16. Functional incontinence may be due to a problem withwhat?
cognitive function | |
autonomic system | |
urinary bladder | |
urethra |
17. Which of the following is not a function of nutrients?
energy for activities | |
raw materials for growth | |
buffer to maintain pH | |
fluid and electrolyte balance |
18. Adenosine triphosphate is produced during all of thefollowing processes, except ______.
Oxidative phosphorylation | |
Kreb's cycle | |
Electron transport | |
Glycation |
19. The digestive system helps create nutritional homeostasis,which of the following is one of the four reasons for nutritionalhomeostasis?
nutrients are formed to supply the energy for vitalfunctions | |
nutrients supply raw materials to synthesize body substances | |
nutrients counteract against blood so that volume ismaintained | |
nutrients tear down worn out substances for later use |
20. Women with _____ percent body fat has an increase risk for ashorter life span and weight related diseases.
18 | |
22 | |
27 | |
31 |
21. What amount of protein should be consumed daily by an olderadult?
.25 gram per kilogram of weight | |
.5 gram per kilogram of weight | |
.75 gram per kilogram of weight | |
1 gram per kilogram of weight |
22. Stress incontinence is much more common in women than in menbecause women have which of the following?
longer urethra | |
premenopausal thinning | |
weakened structures |
23. Which of the following is an age related change affectingthe kidneys?
increase in weight | |
increase in width | |
decrease in area | |
decrease in volume |
24. Postmenopausal decrease in estrogen leads to age relatedchanges of the _________.
Urethra | |
Urinary bladder | |
Ureter | |
Kidney |
25. _______ percent of the working capacity of both kidneys isneeded to maintain homeostasis.
10 | |
20 | |
30 | |
40 |
26. Which of the following is considered a treatment for urinaryincontinence?
surgical removal of the sphincter | |
medications to modify bladder function | |
electric shock therapy |
27. Which reproductive hormone provides a decrease risk ofatherosclerosis?
testosterone | |
relaxin | |
estrogen | |
follicle stimulating hormone |
28. Which form of cancer in the female reproductive system rankssecond in occurrence?
Ovarian | |
Cervical | |
Endometrial | |
Vaginal |
29. Which hormone produced in females seems to stimulate thelibido?
Estrogen | |
Progesterone | |
Testosterone | |
Luteinizing hormone |
30. Which of the following regarding prostate cancer istrue?
it is related to having benign prostatic hypertrophy | |
it is more common in white males | |
testing for prostatic specific antigen is sensitive andspecific | |
it impairs the function of the liver |