BIO 11 Lecture Notes - Lecture 14: Organelle, Conformational Change, Vimentin
3 Sep 2020
School
Department
Course
Professor
Document Summary
Filaments do not span the entire fiber but are arranged in compartments called sarcomeres. Sarcomere- basic functional unit of skeletal muscle fibers. Arrangement of thick and thin filaments sandwiched between two z discs. Because anisotropic (appearance when viewed using polarized light microscopy) Contains the m line, h band and zone of overlap. M line center of the a band; m stands for middle. Proteins of the m line connect the central portion of each filament to the neighboring thick filaments. Stabilize the positions of the thick filaments. H band lighter region on each side of the m line. Contains thick filaments but no thin filaments. Dark region where thin filaments are found between the thick filaments. Z discs bisect the i bands and mark the boundary between adjacent. Made up of proteins called actinin interconnect the thin filaments sarcomeres. Each molecule two golf clubs twisted together. Myosin heads (cross bridges) extend toward the thin filaments, atpase within.
