BIO 11 Lecture Notes - Lecture 7: Rheumatoid Arthritis, Neuromuscular Junction, Diabetes Mellitus Type 1

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T cells bind with antigen infected body cell. Sees a cell that has been marked as foreign. Co-stimulatory signals are present after the binding. Normal self marker that is just messed up somehow (cancer) An antigen presenting cell (it has been infected by something) T cell antigen receptors bind to specific antigen-mhc complexes. T cells binding to other receptors/sites on apc, cytokines, interleukins. T cell binds with antigen infected body cell. Directly attack and kill antigens (class 1 mhc) Use lysis to destroy the infected cell. Activate b cells and cytotoxic t cells. Immunodeficiencies any condition that causes the immune system not to behave. Genetic prevents a person from producing b and t cells. Extremely prone to infection and unable to fight it. Aids: hiv causes the destruction of t lymphocytes. Die of other infection due to the virus. Autoimmune diseases: immune system lost the ability to distinguish self vs non self.

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