BIO 012 Lecture Notes - Lecture 7: Voltage-Gated Potassium Channel, Resting Potential, Action Potential

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5 Oct 2016
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Three types of potentials: (1) resting membrane potential (2) action potential (3) graded potential. These speci c channels usually keep the resting membrane potential of mammals around -65 mv. You cannot have an action potential occur unless the resting membrane potential is already established. An initial amount of na+ oods into the intercellular membrane. Massive rush of na+ into the cell occurs. There is now a signi cant charge (voltage) within the cell. This increase in voltage is due to more and more na+ ooding in through the opened ion channels. Na+ is attempting to achieve equilibrium levels both inside and outside of the cell from diffusion. Between -40mv and -60mv, this equilibrium is almost attained. The membrane has overshot its voltage; it only technically required around -20mv to start an action potential and reach threshold. The gated na+ channels at the point inactivate.

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